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Download PDF by Edited by Andrew D. Blann Edited by Gregory Y. H. Lip: ABC of Antithrombotic Therapy

By Edited by Andrew D. Blann Edited by Gregory Y. H. Lip

Urban health facility, Birmingham, united kingdom. Discusses the reasons and effects of blood clots, how antithrombotic remedy works and its makes use of for sufferers. Addresses bleeding dangers, venous thromboembolism, atrial traumatic inflammation, peripheral vascular disorder, center failure, and anticoagulation. plentiful halftone and colour illustrations. Softcover.

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Alternatively, some surgeons give only low dose aspirin after Valve thrombosis of a bileaflet prosthetic mitral valve Considerations for antithrombotic therapy in patients with valve disease x Assessment of risk for thromboembolic events, which may be patient related or valve prosthesis related x Indications for starting treatment x Choice of antithrombotic agent x Duration of treatment and optimal therapeutic range x Antithrombotic therapy in special circumstances (surgical procedures, pregnancy, and resistance to oral anticoagulants) x Management of treatment failures and complications Types of prosthetic valves and thrombogenicity Type of valve Mechanical Caged ball Single tilting disc Bileaflet Bioprosthetic Heterografts Model Thrombogenicity Starr-Edwards Bjork-Shiley, Medtronic Hall St Jude Medical, Sorin Bicarbon, Carbomedics ++++ +++ Carpentier-Edwards, Tissue Med (Aspire), Hancock II + to + + Homografts ++ + Risk factors for patients with bioprostheses include previous thromboembolic events, atrial fibrillation, enlarged left atrial cavity, and severe cardiac failure 31 ABC of Antithrombotic Therapy surgery in patients with bioprostheses in sinus rhythm (providing aspirin is not contraindicated).

The prothrombotic state in atrial fibrillation: new insights, more questions, and clear answers needed. Am Heart J 2000;140:348-50 x Fuster V, Ryden LE, Asinger RW, Cannom DS, Crijns HJ, Frye RL, et al. ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation. A report of the American College of Cardiology, American Heart Association Task Force on practice guidelines and the European society of Cardiology Committee for Practice Guidelines and Policy Conferences developed in collaboration with the North American Society of Pacing and Electrophysiology.

The figure showing thromboembolic and major haemorrhagic events in the IST is adapted from IST Collaborative Group. Lancet 1997;349:1569-81. 9 Valvar heart disease and prosthetic heart valves Ira Goldsmith, Alexander G G Turpie, Gregory Y H Lip Thromboembolism and anticoagulant related bleeding are major life threatening complications in patients with valvar heart disease and those with prosthetic heart valves. In these patients effective and safe antithrombotic therapy is indicated to reduce the risks of thromboembolism while keeping bleeding complications to a minimum.

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